Lymphovascular invasion in more than one-quarter of small rectal neuroendocrine tumors

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Lymphovascular invasion in more than one-quarter of small rectal neuroendocrine tumors

AIM To identify the frequency, clinicopathological risk factors, and prognostic significance of lymphovascular invasion (LVI) in endoscopically resected small rectal neuroendocrine tumors (NETs). METHODS Between June 2005 and December 2015, 104 cases of endoscopically resected small (≤ 1 cm) rectal NET specimens at Hallym University Sacred Heart Hospital in Korea were retrospectively evaluate...

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Frequent Presence of Lymphovascular Invasion in Small Rectal Neuroendocrine Tumors on Immunohistochemical Analysis.

Rectal neuroendocrine tumors (RNETs) have become common in recent years and are good candidates for endoscopic resection (ER). To achieve clear resection margins, more advanced techniques such as endoscopic submucosal dissection, endoscopic submucosal resection with a ligation device, and cap-assisted endoscopic mucosal resection are available for ER. After ER, lymphovascular invasion (LVI) is ...

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Enhanced detection of lymphovascular invasion in small rectal neuroendocrine tumors using D2‐40 and Elastica van Gieson immunohistochemical analysis

Rectal neuroendocrine tumor (RNET) lymphovascular invasion (LVI) is regarded as an important predictor of nodal metastasis after endoscopic resection (ER). However, little is known about the frequency of immunohistochemical detection of LVI in RNETs. This study was performed to establish the actual detection of LVI rate in RNETs ≤10 mm and to evaluate associated clinical outcomes. We retrospect...

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Are Small Rectal Neuroendocrine Tumors Safe?

Although CT scans do not reflect lymph node metastasis as accurately as a pathologic examination, a case may be regarded as negative for lymph node metastasis if no signs of metastasis appear using CT. 6 Therefore, the authors of the current case 7 reexamined a 7-mm perirectal lymph node identified on a CT scan after EMR for a 8-mm rectal NET. The pathological type of tumor also significantly a...

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Clinical impact of endoscopic ultrasonography for small rectal neuroendocrine tumors.

BACKGROUND/AIMS Endoscopic ultrasonography (EUS) is helpful for evaluating the depth of tumor invasion and lymph node metastasis of rectal neuroendocrine tumors (NETs). The aim of this study was to clarify the clinical impact of EUS for rectal NETs less than 10 mm in diameter. MATERIALS AND METHODS A total of 76 rectal NETs treated at our hospital between June 2006 and March 2013 were reviewe...

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ژورنال

عنوان ژورنال: World Journal of Gastroenterology

سال: 2016

ISSN: 1007-9327

DOI: 10.3748/wjg.v22.i42.9400